Proline

Scientific Name:  (S)-Pyrrolidine-2-carboxylic acid (C5H9NO2).

Other Names:  L-proline, Pro, P, proline.

L-proline is one of the twenty most common amino acids, which are building blocks for proteins within living organisms. 

However, it is the only one of these twenty lacking a primary amine group (-NH2). 

Instead, the nitrogen in proline causes it to become a secondary amine.

Origin of L-proline:  L-proline is derived in biosynthesis from L-glutamate, another amino acid, and its direct precursor is an imino acid P5C (pyrroline-5-carboxylate).

Sources of L-proline: L-proline is often found as an ingredient in energy drinks, though the reason for such inclusion is unknown. 

As a dietary supplement, L-proline can be found in a powdered form for inclusion in protein shakes and other nutritional substances, as well as in capsules (typically 275-500mg dosages).

Home Remedies using Proline:

Benefits and Uses of L-Proline:

L-proline has a sweet flavor with a noticeable aftertaste and is sometimes used to artificially sweeten food and drink products. 

Hydroxylation of proline increases the stability of collagen, making this a critical part of maintaining the connective tissue of many organisms. 

Lack of proper hydroxylation can result in severe diseases like scurvy (spongy gums, liver spots, and bleeding from all mucous membranes).

L-proline can be used to strengthen heart muscles, maintain proper joint and tendon functionality (as an essential compound within cartilage), and to improve and maintain healthy muscle, tissue, and skin. 

L-proline can assist in reparation to skin damage and continuation of a youthful appearance because of its essential inclusion in collagen, which provides softness and elasticity to the skin. 

For individuals on a low protein or vegetarian diet, supplemental L-proline may be necessary for healthy bodily functionality.

Side Effects of L-Proline:

Ingestion of L-proline can cause a slight irritation of the tongue, similar to the effects of Szechuan (Sichuan) pepper. 

No toxicological effects have been discovered in the ingestion of L-proline in any known quantity.

Additional Information for L-Proline:

L-proline is the only amino acid that is readily soluble in alcohol.